Welcome to the Aspergillus fumigatus Af293/CEA10 community sequencing initiative.

The model isolates Af293 and CEA10 have been used by researchers for decades. As these strains have been independently cultured in labs across the globe, they have likely accumulated unique, unstudied mutations. Understanding the extent of this "lab-to-lab" evolution is crucial to reliably compare findings on physiology, pathogenicity, and genetics.

While community sequencing projects have been conducted for other model organisms, this effort is the first of its kind for a filamentous fungus. We believe A. fumigatus is the perfect model pathogen to pioneer this work.

Our goal is to quantify the genetic divergence between all of our labs' parental Af293 and CEA10 strains and create a foundational genomic resource for the entire Aspergillus community. All sequencing data will be provided back to the contributing labs.

To learn more about how to participate, what this involves, and how data will be handled, please visit our Frequently Asked Questions (FAQ) page.